Cystatin C评价肾小球滤过功能的临床应用进展

被引：9

作者：

刘俊峰

杨浏

机构：

[1] 湖北省黄石市第二医院检验科

来源：

国际检验医学杂志 | 2008年 / 29卷 / 05期

关键词：

半胱氨酸蛋白酶抑制剂; 肾小球滤过率; 评价研究;

D O I：

暂无

中图分类号：

R446.61 [免疫学检验方法];

学科分类号：

100208 ;

摘要：

Cystatin C是一种半胱氨酸蛋白酶抑制剂,其相对分子质量小,自由通过肾小球滤过膜,并在近端肾小管重吸收并被完全降解,不再回到血循环中去。血中浓度不受性别、年龄、体重、营养状况、炎症感染、肌肉量等因素的影响,被认为是较为理想的评价肾小球滤过功能内源性标志物。

引用

页码：466 / 468

页数：3

共 7 条

[1] MDRD方程在我国慢性肾脏病患者中的改良和评估 [J].

全国eGFR课题协作组 .

中华肾脏病杂志, 2006, (10) :589-595

[2]

Diagnostic accuracy of cystatin C compared to serum creatinine for the estimation of renal dysfunction in adults and children—A meta-analysis[J] . Juliana F. Roos,Jenny Doust,Susan E. Tett,Carl M.J. Kirkpatrick.Clinical Biochemistry . 2007 (5)

[3] Assessment of glomerular filtration rate in renal transplant patients using serum cystatin C [J].

Xu, H. ;

Lu, Y. ;

Teng, D. ;

Wang, J. ;

Wang, L. ;

Li, Y. .

TRANSPLANTATION PROCEEDINGS, 2006, 38 (07) :2006-2008

[4]

Assessing glomerular filtration rate in renal transplant recipients by estimates derived from serum measurements of creatinine and cystatin C[J] . Lorenz Risch,Andreas R. Huber.Clinica Chimica Acta . 2005 (1)

[5]

β2-Microglobulin and Cystatin C in Type 2 Diabetes: Assessment of Diabetic Nephropathy[J] . S. Aksun,D. ?zmen,B. ?zmen,Z. Parildar,I. Mutaf,N. Turgan,S. Habif,K. Kumanlio?luc,O. Bayindir.Exp Clin Endocrinol Diabetes . 2004 (04)

[6] Evaluation of cystatin C and β-2 microglobulin as markers of renal function in patients with type 2 diabetes mellitus [J].

Mojiminiyi, OA ;

Abdella, N .

JOURNAL OF DIABETES AND ITS COMPLICATIONS, 2003, 17 (03) :160-168

[7]

Cystatin C assay for the detection of renal dysfunction in Chinese renal transplant recipients[J] . Fu Keung Li,Stephen Ka Nung Ho,Terence Pok Siu Yip,Kai Chung Tse,Tak Mao Chan,Kar Neng Lai.Clinica Chimica Acta . 2002 (1)

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