熊果酸衍生物构效关系研究进展

被引:7
作者
李彩莲
冯锋
机构
[1] 中国药科大学天然药物化学教研室
关键词
熊果酸; 结构修饰; 构效关系;
D O I
暂无
中图分类号
R284 [中药化学];
学科分类号
摘要
综述了近年来对熊果酸的结构修饰及其衍生物构效关系的研究进展。熊果酸是一种广泛存在于天然植物中的五环三萜类化合物,具有抗肿瘤、降血糖、抗炎、抗HIV等药理活性,故而受到研究人员的广泛关注。对熊果酸进行结构修饰及构效关系探索,以获得高效低毒的候选化合物,已成为该化合物的研究热点之一。
引用
收藏
页码:23 / 29
页数:7
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