脂质筏神经鞘磷脂在T细胞活化中的作用

被引:3
作者
黄成日
机构
[1] 延边大学附属医院妇产科
关键词
D O I
暂无
中图分类号
R392.11 [免疫分子生物学(免疫化学)];
学科分类号
100108 [医学免疫学];
摘要
<正>机体通过正确地调节活化免疫细胞的信号传递,抵抗入侵的病原微生物。其中获得性免疫起主要作用,主体为T淋巴细胞或B淋巴细胞。细胞膜上的T细胞受体集中在免疫突触的中央,与抗原提呈细胞结合形成免疫突触[1]。1972年Nicolson提出细胞膜液态镶嵌模型,当时这一重大发现在学界引起了轰动。随着对细胞膜研究的深入,近年,脂质组学逐渐受到了关注。1997年Simons和Ikonen提
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页码:1574 / 1577
页数:4
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