转化生长因子β与糖尿病肾病的发病机理

被引:9
作者
张嘉
张家庆
机构
[1] 第二军医大学附属长海医院
[2] 第二军医大学附属长海医院 上海
[3] 不详
关键词
糖尿病肾病; mRNA; AGEs; 系膜细胞; 糖尿病性肾病; 肾疾病; 高糖培养; TGF; 肾小球系膜; 细胞外基质; 基质(细胞); 肾脏组织;
D O I
暂无
中图分类号
R692.9 [其他疾病];
学科分类号
摘要
<正> 肾脏病变是最常见和最严重的糖尿病慢性并发症之一。糖尿病肾病的主要病理变化包括肾小球和肾小管的肥大、肾小球及肾小管基底膜增厚、肾小球系膜区细胞外基质堆积以及肾小管间质的硬化,其发生机制尚不十分明确。近年来转化生长因子β(transforminggrowth factor-β,TGF-β)的介导作用已越来越受到人们的重视,我们对TGF-β与糖尿病肾病发病的关系作一综述。
引用
收藏
页码:62 / 64
页数:3
相关论文
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