绝经前女性冠心病患者的临床和冠状动脉造影特点

被引：14

作者：

邱洪

吴元

窦克非

陈珏

杨伟宪

胡奉环

慕朝伟

戴军

张沛

刘海波

姚民

袁晋青

秦学文

吴永健

李建军

乔树宾

陈纪林

杨跃进

高润霖

陈在嘉

机构：

[1] 中国医学科学院北京协和医学院心血管病研究所阜外心血管病医院冠心病诊治中心

来源：

中国循环杂志 | 2009年 / 24卷 / 06期

关键词：

绝经前; 女性; 冠脉造影; 临床特点;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

100201 [内科学];

摘要：

目的:分析绝经前女性冠心病(CAD)患者的临床和冠状动脉(冠脉)造影特点。方法:对比2004-04至2007-12所有第一次因胸部不适而行冠脉造影的绝经前565例患者,根据造影结果分为绝经前冠心病组280例,平均年龄(44.12±4.48)岁,绝经前正常组285例,平均年龄(44.24±3.48)岁,绝经后经冠脉造影确定冠心病的患者为绝经后冠心病组721例,平均年龄(58.09±1.44)岁,分析其临床和冠脉造影特点。结果:绝经前冠心病组与绝经后冠心病组相比,高血压(55%比66%)、2型糖尿病(15.0%比31.5%)和高脂血症(23.9%比37.4%)的发生率显著减少,P均<0.05。绝经前冠心病组比绝经后冠心病组单支病变的发生率显著增高(43.2%比26.9%,P<0.001),差异有统计学意义;而三支病变的发生率则显著降低(20.4%比33.8%,P<0.001);左主干(2.9%比1.1%,P=0.048)和前降支近端(50.4%比38.6%,P<0.001)重度狭窄(狭窄≥90%)的发生率却显著增高,差异有统计学意义。结论:绝经前女性具有典型胸痛症状,冠脉造影常显示严重的冠脉狭窄病变,而且这些病变常位于左主干和前降支近端。

引用

页码：410 / 413

页数：4

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