乳杆菌属与宫颈癌的研究进展

被引:8
作者
王子璇 [1 ]
赵茜茜 [2 ]
高翔 [1 ,3 ]
董春楠 [1 ,3 ]
贾娴娴 [1 ,3 ]
机构
[1] 河北医科大学病原生物学教研室
[2] 河北医科大学医学影像学院
[3] 中国医学科学院消化道微生态药理毒理学创新单元
关键词
子宫颈上皮非典型增生; 宫颈肿瘤; 乳杆菌; 阴道微生态;
D O I
暂无
中图分类号
R737.33 [子宫肿瘤];
学科分类号
100112 [医学生物化学与分子生物学];
摘要
宫颈癌是女性常见的恶性肿瘤。阴道内正常菌群的改变常导致多种妇科疾病,包括宫颈癌。最新的研究表明,乳杆菌可能在宫颈癌的发生和发展中发挥着重要作用。本文经过鉴定、筛选和验证,共纳入25篇文章,分析梳理以乳杆菌与宫颈癌为关键词的相关文献,包括临床研究和实验研究,构建乳杆菌拮抗宫颈癌发生、发展的关联网络,提供乳杆菌治疗宫颈癌的重要机制与靶点,为进一步的研究提供了方向和策略。
引用
收藏
页码:1954 / 1957
页数:4
相关论文
共 22 条
[1]
A global drive to eliminate cervical cancer..[J].DeWeerdt Sarah.Nature.2020, 7804
[2]
Vaginal microbiomes and ovarian cancer: a review [J].
Xu, Jinyun ;
Peng, Jing-Jie ;
Yang, Wenqing ;
Fu, Kun ;
Zhang, Yu .
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 10 (03) :743-756
[3]
Comparative Genomics of Lactobacillus crispatus from the Gut and Vagina Reveals Genetic Diversity and Lifestyle Adaptation [J].
Zhang, Qiuxiang ;
Zhang, Lili ;
Ross, Paul ;
Zhao, Jianxin ;
Zhang, Hao ;
Chen, Wei .
GENES, 2020, 11 (04)
[4]
Cervicovaginal microbiome and natural history of HPV in a longitudinal study [J].
Usyk, Mykhaylo ;
Zolnik, Christine P. ;
Castle, Philip E. ;
Porras, Carolina ;
Herrero, Rolando ;
Gradissimo, Ana ;
Gonzalez, Paula ;
Safaeian, Mahboobeh ;
Schiffman, Mark ;
Burk, Robert D. .
PLOS PATHOGENS, 2020, 16 (03)
[5]
Surface-layer protein from Lactobacillus acidophilus NCFM attenuates tumor necrosis factor-α-induced intestinal barrier dysfunction and inflammation.[J].Huifang Wang;Qiuxiang Zhang;Yuhan Niu;Xin Zhang;Rongrong Lu.International Journal of Biological Macromolecules.2019,
[6]
Safety and efficacy of mucosal immunotherapy using human papillomavirus (HPV) type 16 E7-expressing Lactobacillus-based vaccine for the treatment of high-grade squamous intraepithelial lesion (HSIL): the study protocol of a randomized placebo-controlled clinical trial (MILACLE study) [J].
Ikeda, Yuji ;
Uemura, Yukari ;
Asai-Sato, Mikiko ;
Nakao, Takehiro ;
Nakajima, Takahiro ;
Iwata, Takashi ;
Akiyama, Azusa ;
Satoh, Toyomi ;
Yahata, Hideaki ;
Kato, Kiyoko ;
Maeda, Daichi ;
Aoki, Daisuke ;
Kawana, Kei .
JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 2019, 49 (09) :877-880
[7]
Gut microbiome and cancer immunotherapy.[J].Weina Li;Yu Deng;Qian Chu;Peng Zhang.Cancer Letters.2019,
[8]
The distribution and prevalence of human papillomavirus in women in mainland China [J].
Li, Kemin ;
Li, Qingli ;
Song, Liang ;
Wang, Danqing ;
Yin, Rutie .
CANCER, 2019, 125 (07) :1030-1037
[9]
Adherence of Lactobacillus salivarius to HeLa Cells Promotes Changes in the Expression of the Genes Involved in Biosynthesis of Their Ligands..[J].Martín Carla;Fernández-Vega Iván;Suárez Juan E;Quirós Luis M.Frontiers in immunology.2019,
[10]
Role of Lactobacillus in cervical cancer [J].
Yang, Xi ;
Da, Miao ;
Zhang, Wenyuan ;
Qi, Quan ;
Zhang, Chun ;
Han, Shuwen .
CANCER MANAGEMENT AND RESEARCH, 2018, 10 :1219-1229