溶肉瘤素抑制小白鼠肿瘤的机制

被引:1
作者
顾国彦
吕家鸿
胡兆庆
机构
[1] 中国科学院实验生物研究所,中国科学院实验生物研究所,中国科学院实验生物研究所,
关键词
溶肉瘤素; 疗效; 腹水瘤; 氮芥; 皮下注射; 热溶; 恩比兴; 氮芥化合物; 浸蚀; 艾氏腹水瘤细胞; 酸溶性; 小白鼠;
D O I
暂无
中图分类号
学科分类号
摘要
<正> 前言溶肉瘤素(Sarcolysine)抑制某些移植瘤的生长,非常显著,但对于很多肿瘤的疗效不大(Larionov,1957;Koller 和 Veronesi,1956)。Németh 等(1958)应用此药于小鼠艾氏腹水瘤,只能抑制25%左右。Koller 和 Veronesi(1956)认为此药对于肉瘤 S180没
引用
收藏
页码:185 / 198
页数:14
相关论文
共 30 条
[1]  
Effect of cell division inhibitors on the phosphorus metabolism of growing culture of Saccharomyces cerevisiae. Katchman,B.J,Fetty,W.O,and Susch,K.A. Journal of Bacteriology . 1959
[2]  
The action of the phenylalanine mustards and of several homologs on mouse melanoma. Luck,J.M. Cancer Research . 1957
[3]  
A simple and accurate method for the determination of chloride in biological fluids. Schales O, Schales SS. Journal of Biological Chemistry . 1941
[4]  
The reactions of the"radiomimetic"alkylating agent with macromolecules in vitro. Stacey,K.A,Cobb,M,Cousens,F,and Alexander,P. Anna.N.Y.Acad.Sci . 1958
[5]  
Some effects of nitrogen and sulphur mustard on the metabolism of nucleic acids in mammalian cells. Drysdale RB, et al. British Journal of Cancer . 1958
[6]  
The distribution of radioactivity in tissues of the rat following the administration of a nitrogen mustard derivative(p-di-(2-chloroethyl)amino-dl-phenyl[β14 C]alanine). Cohn,P. Brit.J. Cancer . 1957
[7]   提高溶肉瘤素疗效的简报 [J].
吕家鸿 ;
顾国彦 ;
胡兆庆 ;
彭素芬 .
科学通报, 1960, (03) :90-91
[8]  
The effect of nitrogen mustards on the metabolism of nucleicacid in the hematopoietic tissue of the rabbit. Lowrance P.C,and Carter,C.E. J.Cell.Comp.Physiol . 1950
[9]  
The effects of a nitrogen mustard derivative of phenylalanine on experimental tumor. Koller,P.C,and Veronesi,U. British Journal of Cancer . 1956
[10]  
The effect of chlorambucil on growth and metabolism. Youug,R.S,Hurwitz,L,and Goldenthal,E.I. J.Cell.Comp.Physiol . 1958