人脑循环临界关闭压、有效脑灌注压无创测定方法的研究

被引:10
作者
朱良付
黄如训
高庆春
陈颖贤
盛文利
曾进胜
机构
[1] 中山大学附属第一医院神经脑血管专科
[2] 广州医学院附属第二医院神经科学研究所
关键词
超声检查,多普勒,经颅; 血压; 临界关闭压; 脑灌注压;
D O I
暂无
中图分类号
R445.1 [超声波诊断];
学科分类号
摘要
目的探讨人脑循环临界关闭压(criticalclosingpressure,CCP)和有效脑灌注压(cerebral perfusionpressure,CPP)的无创测定方法。方法选择符合入组要求的青年健康志愿者32例,应用经颅超声多普勒、无创血压监测仪持续记录大脑中动脉血流流速、桡动脉血压,用动态压力流量关系法中的常规法和傅立叶变换法分别测得两组CCP和CPP值。结果用常规法测定CCP有4例为负值,后经傅立叶变换法测定均为正值。常规法测定的CCP为(13.05±8.24)mmHg(1mmHg=0.133kPa),傅立叶变换法测定的CCP平均为(19.68±9.30)mmHg,较常规法测定值高(t=-2.904,P=0.005)。常规法测定的有效CPP为(66.76±9.14)mmHg,傅立叶变换法测定的有效CPP为(60.79±10.12)mmHg,两者差异有显著性意义(t=2.382,P=0.021)。结论临床无创测定CCP和有效CPP应该采用傅立叶变换法。
引用
收藏
页码:366 / 369
页数:4
相关论文
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