腹腔镜卵巢子宫内膜异位囊肿剔除手术对卵巢储备功能影响的研究

被引：20

作者：

张芳

罗军

唐密

机构：

[1] 湖南省妇幼保健院妇三科

来源：

中国医师杂志 | 2015年 / 17卷 / 05期

关键词：

腹腔镜检查; 卵巢囊肿/外科学/病理生理学; 子宫内膜异位症/外科学/病理生理学; 卵巢/药物作用;

D O I：

暂无

中图分类号：

R713.6 [卵巢手术];

学科分类号：

摘要：

目的探讨腹腔镜卵巢子宫内膜异位囊肿(巧囊)剔除手术对卵巢储备功能的影响。方法选择巧囊腹腔镜囊肿剔除术患者142例为研究组, 另选卵巢成熟性囊性畸胎瘤150例为对照组, 均行腹腔镜卵巢囊肿剔除术。术前检测基础内分泌水平及血清抗苗勒管激素(AMH), 术后分析囊壁组织病理切片、计数残留卵巢及卵泡组织的改变;患者出院后进行随访6个月, 观察巧囊剔除后对卵巢储备功能的影响。结果两组患者年龄、BMI、囊肿直径、基础卵泡生成素(FSH)、雌二醇(E2)及卵泡生成素/黄体生成素(FSH/LH)比较差异均无统计学意义(P>0.05), 而血清AMH水平低于对照组[(2.48±1.05)ng/ml vs (3.35±1.15)ng/ml, P<0.05=。Ⅲ、Ⅳ期患者AMH水平明显低于Ⅰ、Ⅱ期患者[(2.28±1.17)ng/ml vs (2.96±1.76)ng/ml, P<0.05==;术后6个月研究组血清AMH水平低于对照组[(2.05±0.89)ng/ml vs (2.98±1.27)ng/ml, P<0.05=。研究组病理切片囊壁残留组织及卵泡残留量高于对照组(P<0.05=。结论巧囊本身影响卵巢储备功能, 其病理分期级别越高对卵巢储备影响越大;腹腔镜巧囊剔除术对卵巢储备功能仍有一定的影响。

引用

页码：732 / 734

页数：3

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