树鼩的社会挫败抑郁模型

被引：12

作者：

祁可可 ^{[1
,2
]}

冯敏 ^{[1
,2
]}

孟肖路 ^{[1
,2
]}

李勇辉 ^{[1
]}

朱宁 ^{[1
]}

隋南 ^{[1
]}

机构：

[1] 中国科学院心理健康重点实验室,中国科学院心理研究所

[2] 中国科学院研究生院

来源：

心理科学进展 | 2012年 / 20卷 / 11期

关键词：

抑郁症; 树鼩; 社会挫败; 表面效度; 预测效度; 结构效度;

D O I：

暂无

中图分类号：

B841 [心理学研究方法];

学科分类号：

040201 ;

摘要：

创制理想的动物模型是突破抑郁症研究的技术难点之一。来自进化研究的证据提示,树鼩属灵长类近缘的一种小型动物,具有较为发达的神经系统和与人类相似的应激系统,因而可能成为创制精神疾病行为模型的较佳选择。已有的研究表明,树鼩社会挫败模型可能具有比啮齿类更好的表面效度、预测效度及结构效度。由于树鼩与人类的近缘关系,对其抑郁行为的脑机制研究或药物评价可能更具潜在价值。但是,该模型仍有待进一步利用、拓展和完善。

引用

页码：1787 / 1793

页数：7

共 24 条

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