胰腺癌发病的高危因素分析

被引:7
作者
李凤茹
江华
机构
[1] 同济大学附属东方医院老年医学科
关键词
胰腺癌; 危险因素; 高危人群;
D O I
暂无
中图分类号
R735.9 [胰腺肿瘤];
学科分类号
100214 ;
摘要
胰腺癌的发病同多数肿瘤一样,是环境因素与遗传因素共同作用的结果,研究胰腺癌的高危因素,并对高危人群进一步筛查是提高早期诊断率、降低死亡率的有效措施之一。其中吸烟是胰腺癌发病的独立危险因素,长期的尼古丁摄入促使胰腺癌的发生,饮食方式可能也很重要,但很难对其进行评估。胰腺癌的发病率随着年龄的增加而增加,男性好发,与糖尿病、慢性胰腺炎等疾病有着密切的联系,胰腺癌发生之前有很多分子标志物的变化,对这些标志物的筛查可能会在将来的早期诊断中发挥重要作用。
引用
收藏
页码:331 / 334
页数:4
相关论文
共 10 条
[1]   Incidence of Pancreatic Cancer in Chinese Patients with Chronic Pancreatitis [J].
Wang, Wei ;
Liao, Zhuan ;
Li, Gang ;
Li, Zhao-Shen ;
Chen, Jie ;
Zhan, Xian-Bao ;
Wang, Luo-Wei ;
Liu, Feng ;
Hu, Liang-Hao ;
Guo, Yan ;
Zou, Duo-Wu ;
Jin, Zhen-Dong .
PANCREATOLOGY, 2011, 11 (01) :16-23
[2]  
Cigarette smoking, environmental tobacco smoke exposure and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition[J] . Int. J. Cancer . 2010 (10)
[3]  
Alcohol drinking and pancreatic cancer risk: a meta‐analysis of the dose‐risk relation[J] . IreneTramacere,LorenzaScotti,MazdaJenab,VincenzoBagnardi,RinoBellocco,MatteoRota,GiovanniCorrao,FrancescaBravi,PaoloBoffetta,CarloLa Vecchia.Int. J. Cancer . 2010 (6)
[4]  
Different Markers of Alcohol Consumption, Smoking and Body Mass Index in Relation to Risk of Pancreatic Cancer[J] . Dorthe Johansen,Anders Borgstr?m,Bj?rn Lindkvist,Jonas Manjer.Pancreatology . 2009 (5)
[5]  
Tobacco smoking, alcohol consumption and pancreatic cancer risk: A case-control study in Italy[J] . R. Talamini,J. Polesel,S. Gallus,L. Dal Maso,A. Zucchetto,E. Negri,C. Bosetti,E. Lucenteforte,G. Boz,S. Franceschi,D. Serraino,C. La Vecchia.European Journal of Cancer . 2009 (2)
[6]  
Global Cancer Statistics, 2002[J] . D. MaxParkin,FreddieBray,J.Ferlay,PaolaPisani.CA: A Cancer Journal for Clinicians . 2009 (2)
[7]  
Genome-wide profiling at methylated promoters in pancreatic adenocarcinoma[J] . Noriyuki Omura,Chung-Pin Li,Ang Li,Seung-Mo Hong,Kimberly Walter,Antonio Jimeno,Manuel Hidalgo,Michael Goggins.Cancer Biology & Therapy . 2008 (7)
[8]  
Epidemiology and risk factors for pancreatic cancer[J] . Albert B. Lowenfels.Best Practice & Research Clinical Gastroenterology . 2005 (2)
[9]   Environmental factors and risk of pancreatic cancer [J].
Lowenfels, AB ;
Masionneuve, P .
PANCREATOLOGY, 2003, 3 (01) :1-7
[10]  
Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies .2 Huxley,R,Ansary-Moghaddam,A,Berrington de Gonzalez,A,Barzi,F,Woodward,M. Br J Cancer . 2005