脂联素与代谢综合征

被引:17
作者
王绍云
机构
[1] 上海第二医科大学附属瑞金医院
关键词
脂联素; 胰岛素抵抗; PPARγ;
D O I
暂无
中图分类号
R589 [代谢病];
学科分类号
摘要
脂联素 (adiponectin)是脂肪细胞特异性的一种血浆激素蛋白 ,其基因定位于 3q2 7。脂联素与肥胖、2型糖尿病、胰岛素抵抗、动脉粥样硬化以及糖尿病的血管病变等都有一定的相关性 ,在X综合征的发病过程中可能起着重要的作用 ,补充脂联素可能为胰岛素抵抗及 2型糖尿病的治疗提供一种手段。脂联素在血细胞形成和免疫反应中发挥负调控作用。过氧化物酶体增殖物激活受体γ(PPARγ)配基增加脂联素的表达及其在血浆中的浓度
引用
收藏
页码:161 / 163
页数:3
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