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肾性血管活性因子与糖尿病肾病研究进展

被引：2
作者：
刘长波
汪华林
机构：
[1] 广州医学院第一附属医院泌尿内科
来源：
国际泌尿系统杂志 | 2006年 / 05期
关键词：
糖尿病肾病;
D O I：
暂无
中图分类号：
R692.9 [其他疾病];
学科分类号：
摘要：
AngⅡ具有多种生物学效应,包括激活细胞内第二信使、转录因子、细胞外基质蛋白、各种生长因子和细胞因子,从而导致糖尿病肾脏发生结构和功能改变。但RAS阻断剂却不能阻止糖尿病人进展到终末期肾病。评估其与AngⅡ相似且功能独特的血管活性因子将有助于了解它们在糖尿病肾病进展中的可能作用。进一步研究包括血管肽酶、内皮素、尾加压素Ⅱ及RAS等在内的血管活性物质可能为治疗糖尿病肾病提供新的策略。
引用
收藏
页码：701 / 704
页数：4
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