红霉素生物合成的分子生物学

被引:27
作者
张部昌
赵志虎
马清钧
机构
[1] 军事医学科学院生物工程研究所
[2] 军事医学科学院生物工程研究所 北京
[3] 北京
关键词
红霉素; 抗生素; 生物合成; 聚酮; 大环内酯;
D O I
暂无
中图分类号
Q936 [微生物生物化学];
学科分类号
071010 ;
摘要
近年来 ,国外对大环内酯类抗生素生物合成和基因工程的研究非常迅速 ,不仅认识了许多抗生素生物合成的过程 ,而且利用基因工程技术改造抗生素生物合成基因 ,合成了 10 0多种非天然的“天然”抗生素。抗生素生物合成的分子生物学是抗生素基因工程的基础。本文全面介绍了大环内酯类抗生素的代表———红霉素生物合成分子生物学的历史、现状及发展趋势。
引用
收藏
页码:151 / 160
页数:10
相关论文
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