视黄醇结合蛋白4研究进展

被引:4
作者
丁云川
机构
[1] 天津市宝坻区人民医院内分泌科
关键词
视黄醇结合蛋白4; 肥胖; 胰岛素抵抗; 心血管疾病;
D O I
暂无
中图分类号
R341 [];
学科分类号
1001 ;
摘要
<正>视黄醇结合蛋白(retinol-binding protein,RBP)是一类相对分子质量为2l Ku的维生素A运载蛋白,RBP4是新近发现的脂肪细胞因子之一。多项研究表明,其水平升高和胰岛素抵抗、2型糖尿病、肥胖以及心血管疾病危险因素(如脂谱的改变)有
引用
收藏
页码:373 / 375
页数:3
相关论文
共 7 条
[1]  
Serum retinol‐binding protein 4 is not increased in obesity or obesity‐associated type 2 diabetes mellitus, but is reduced after relevant reductions in body fat following gastric bypass[J] . J.Gómez‐Ambrosi,A.Rodríguez,V.Catalán,B.Ramírez,C.Silva,F.Rotellar,M. J.Gil,J.Salvador,G.Frühbeck.Clinical Endocrinology . 2008 (2)
[2]   An RBP4 promoter polymorphism increases risk of type 2 diabetes [J].
van Hoek, M. ;
Dehghan, A. ;
Zillikens, M. C. ;
Hofman, A. ;
Witternan, J. C. ;
Sijbrands, E. J. G. .
DIABETOLOGIA, 2008, 51 (08) :1423-1428
[3]   Retinol binding protein-4 levels and clinical features of type 2 diabetes patients [J].
Takebayashi, Kohzo ;
Suetsugu, Mariko ;
Wakabayashi, Sadao ;
Aso, Yoshimasa ;
Inukai, Toshihiko .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (07) :2712-2719
[4]  
Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with type 2 diabetes or coronary artery disease[J] . M. Eynatten,P. M. Lepper,D. Liu,K. Lang,M. Baumann,P. P. Nawroth,A. Bierhaus,K. A. Dugi,U. Heemann,B. Allolio,P. M. Humpert.Diabetologia . 2007 (9)
[5]   Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes [J].
Gavi, Shai ;
Stuart, Louise M. ;
Kelly, Patricia ;
Melendez, Mark M. ;
Mynarcik, Dennis C. ;
Gelato, Marie C. ;
McNurlan, Margaret A. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (05) :1886-1890
[6]   Serum retinol-binding protein 4 is reduced after weight loss in morbidly obese subjects [J].
Haider, Dominik G. ;
Schindler, Karin ;
Prager, Gerhard ;
Bohdjalian, Arthur ;
Luger, Anton ;
Wolzt, Michael ;
Ludvik, Bernhard .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (03) :1168-1171
[7]  
Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids. Vu-Dac, N,P Gervois,I.P. Torra, et al. The Journal of Clinical Investigation . 1998