中脑导水管周围灰质参与疼痛发病机制的磁共振研究进展

被引:12
作者
贾志华
于生元
机构
[1] 北京解放军总医院神经内科
关键词
中脑导水管周围灰质; 疼痛; 磁共振成像;
D O I
暂无
中图分类号
R741 [神经病学];
学科分类号
100204 [神经病学];
摘要
疼痛是一种主观性不愉快感受,临床复杂及疗效不确定,而中脑导水管周围灰质作为上行痛觉传导及下行痛觉调节系统的重要组成部分,其与疼痛关系越来越受到关注。磁共振成像作为一种非创伤性检查,对于PAG在疼痛发生及调节过程中的病理机制阐述上发挥了重要作用,研究提示某些改变具有共性,而某些改变具有特异性。本文主要介绍与疼痛相关的PAG结构及功能的磁共振改变的研究进展。
引用
收藏
页码:454 / 457
页数:4
相关论文
共 16 条
[1]
慢性疼痛性别差异的静息态脑功能成像研究 [J].
陈俊 ;
葛缅 ;
刘波 ;
刘岘 .
中国疼痛医学杂志, 2013, 19 (12) :714-718
[2]
大鼠中脑导水管周围灰质-中缝大核-三叉神经脊束核尾侧亚核通路的电镜研究 [J].
李云庆 ;
施际武 .
神经解剖学杂志, 1994, (03)
[3]
Intrinsic functional connectivity of periaqueductal gray subregions in humans [J].
Coulombe, Marie-Andree ;
Erpelding, Nathalie ;
Kucyi, Aaron ;
Davis, Karen Deborah .
HUMAN BRAIN MAPPING, 2016, 37 (04) :1514-1530
[4]
Functional MRI of migraine [J].
Schwedt, Toddi ;
Chiang, Chia-Chun ;
Chong, Catherine D. ;
Dodick, David W. .
LANCET NEUROLOGY, 2015, 14 (01) :81-91
[5]
Structural abnormality of the hippocampus associated with depressive symptoms in heart failure rats.[J].Hideaki Suzuki;Akira Sumiyoshi;Yasuharu Matsumoto;Ben A. Duffy;Takeo Yoshikawa;Mark F. Lythgoe;Kazuhiko Yanai;Yasuyuki Taki;Ryuta Kawashima;Hiroaki Shimokawa.NeuroImage.2015,
[6]
Disrupted functional connectivity of the periaqueductal gray in chronic low back pain.[J].Rongjun Yu;Randy L. Gollub;Rosa Spaeth;Vitaly Napadow;Ajay Wasan;Jian Kong.NeuroImage: Clinical.2014,
[7]
Gray matter alterations in chronic pain: A network-oriented meta-analytic approach.[J].Franco Cauda;Sara Palermo;Tommaso Costa;Riccardo Torta;Sergio Duca;Ugo Vercelli;Giuliano Geminiani;Diana M.E. Torta.NeuroImage: Clinical.2014,
[8]
The contribution of sensory system functional connectivity reduction to clinical pain in fibromyalgia [J].
Pujol, Jesus ;
Macia, Didac ;
Garcia-Fontanals, Alba ;
Blanco-Hinojo, Laura ;
Lopez-Sola, Marina ;
Garcia-Blanco, Susana ;
Poca-Dias, Violant ;
Harrison, Ben J. ;
Contreras-Rodriguez, Oren ;
Monfort, Jordi ;
Garcia-Fructuoso, Ferran ;
Deus, Joan .
PAIN, 2014, 155 (08) :1492-1503
[9]
The Perception and Endogenous Modulation of Pain.[J].Michael H. Ossipov;á. M. Pastor;C. Porcaro;D. K. Ryugo.Scientifica.2012,
[10]
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010.[J].Theo Vos;Abraham D Flaxman;Mohsen Naghavi;Rafael Lozano;Catherine Michaud;Majid Ezzati;Kenji Shibuya;Joshua A Salomon;Safa Abdalla;Victor Aboyans;Jerry Abraham;Ilana Ackerman;Rakesh Aggarwal;Stephanie Y Ahn;Mohammed K Ali;Mohammad A AlMazroa;Miriam Alvarado;H Ross Anderson;Laurie M Anderson;Kathryn G Andrews;Charles Atkinson;Larry M Ba