正常人脑静息态功能磁共振的脑功能连接

被引：17

作者：

石庆丽 ^{[1
]}

燕浩 ^{[2
]}

陈红燕 ^{[3
]}

王凯 ^{[3
]}

姚婧璠 ^{[4
]}

韩在柱 ^{[5
]}

张玉梅 ^{[4
]}

张贵云 ^{[1
]}

高玉苹 ^{[1
]}

机构：

[1] 北京市平谷区医院神经内科

[2] 西安电子科技大学外国语学院

[3] 首都医科大学附属北京天坛医院医学影像中心

[4] 首都医科大学附属北京天坛医院神经内科

[5] 北京师范大学认知与学习国家重点实验室

来源：

中国康复理论与实践 | 2014年 / 06期

关键词：

静息态功能磁共振成像; 脑功能连接; 独立成分分析;

D O I：

暂无

中图分类号：

R445.2 [核磁共振成像];

学科分类号：

100231 [临床病理学];

摘要：

目的探讨正常人脑静息状态下的不同专属脑网络间的连接强度及其意义。方法选取36名健康受试者进行静息态功能磁共振(rs-fMRI)扫描,采用独立成分分析(ICA)方法分离静息状态五大专属性功能脑网络,将五大脑网络分别作为感兴趣区,并采用多变量Granger因果分析方法(GCA)分析相关脑网络之间的功能因果连接的强度关系。采用SPM 5.0软件进行分析处理。结果应用ICA方法得到5个经典的正常人静息态脑网络成分,分别为默认网络(DMN)、记忆网络(MeN)、运动网络(MoN)、听觉网络(AN)和执行控制网络(ECN)。GCA分析表明,DMN和其余4个网络之间、MeN和ECN之间、AN和MoN之间、ECN和AN之间均存在显著的因果联系。结论正常人在静息状态下存在特定的脑功能连接网络,且这些网络之间有着显著的因果联系。

引用

页码：543 / 547

页数：5

共 15 条

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