白藜芦醇的抗肿瘤药理作用研究新进展

被引：9

作者：

巫志峰

赵瑞芝

机构：

[1] 广东省中医院中心实验室

[2] 广东省中医院中心实验室广州

[3] 广州

来源：

中南药学 | 2004年 / 03期

关键词：

白藜芦醇; 细胞株; 凋亡; 抗肿瘤;

D O I：

暂无

中图分类号：

R285 [中药药理学];

学科分类号：

摘要：

<正> 白藜芦醇(3,4′,5,-三羟基二苯乙烯;resveratrol)是一种活性非黄酮多酚物质,广泛存在于葡萄、花生、虎杖等天然食物或约物中,一般认为其是一种植物抗毒素,在植物受到病原性进攻和环境恶化时产生的。白藜芦醇具有显著的抗炎、抗突变、抗氧化、抗自由基以及抑制血小板聚集的作用,可预防动脉硬化,防止冠心病;降低血清和肝脏的脂质,保护肝脏,被确定为虎杖等中药的有效成分和质控指标之一;在原料提供方面,目前研究者已经改进从葡萄提取方法,并在多种植物中发现了白藜芦醇可供制备提取,并将应用化学合成等方式进行生产,甚至对白藜芦醇及其同系物进行了合成工艺及生物活性评价。

引用

页码：167 / 169

页数：3

共 10 条

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