盐酸氨基葡萄糖联合塞来昔布对膝关节骨性关节炎的临床疗效观察

被引：47

作者：

李伟 ^{[1
]}

赵育红 ^{[1
]}

武长江 ^{[2
]}

刘光宇 ^{[1
]}

刘涛 ^{[1
]}

郭晓东 ^{[3
]}

机构：

[1] 河北承德县中医院

[2] 承德县医院

[3] 解放军第医院

来源：

现代生物医学进展 | 2015年 / 15卷 / 02期

关键词：

盐酸氨基葡萄糖; 塞来昔布; 膝关节; 骨性关节炎;

D O I：

10.13241/j.cnki.pmb.2015.02.021

中图分类号：

R684.3 [关节炎];

学科分类号：

100220 [骨科学];

摘要：

目的:观察盐酸氨基葡萄糖联合塞来昔布治疗膝关节骨性关节炎的效果及对不同程度关节炎Lequesne评分的影响,为关节炎的临床治疗提供参考。方法:选取2012年6月至2014年3月我院收治的膝关节骨性关节炎患者60例,根据治疗方法不同,将所选患者分为观察组和对照组,每组30例。对照组患者给予盐酸氨基葡萄糖单药治疗,观察组患者给予盐酸氨基葡萄糖和塞来昔布联合治疗。观察两种治疗方案的不良反应发生率,比较两组患者治疗前后的Lequesne评分。结果:对照组患者不良反应的发生率为26.67%,观察组为23.33%,差异无统计学意义(P>0.05)。两组患者治疗后的Lequesne评分均低于治疗前,且观察组患者Lequesne评分显著低于对照组,差异具有统计学意义(P<0.05)。观察组不同程度膝关节骨性关节炎患者的Lequesne评分均显著低于对照组,差异具有统计学意义(P<0.05)。结论:盐酸氨基葡萄糖联合塞来昔布治疗膝关节骨性关节炎具有良好的临床效果,应进一步推广应用。

引用

页码：281 / 283

页数：3

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