一氧化氮供体型新药研究

被引：4

作者：

张奕华

彭司勋

机构：

[1] 中国药科大学新药研究中心

来源：

药学学报 | 2009年 / 11期

基金：

高等学校博士学科点专项科研基金;

关键词：

一氧化氮; 信使物质; 效应分子; NO供体型药物;

D O I：

10.16438/j.0513-4870.2009.11.010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

一氧化氮(NO)作为信使物质或效应分子在体内发挥极其重要的生理作用,NO生成不足或NO信号传导异常与多种疾病的形成和发展密切相关。因此,设计和研究NO供体型药物已成为新药发现的重要策略之一。本文作者结合自己的科研实践,综述近年来NO供体型新药的研究进展。

引用

页码：1200 / 1210

页数：11

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