The endocrine regulation network of growth hormone synthesis and secretion in fish: Emphasis on the signal integration in somatotropes

被引:8
作者
LI WenSheng & LIN HaoRan State Key Laboratory of Biocontrol
Institute of Aquatic Economic Animals and the Guangdong Provincial Key Laboratory for Aquatic Economic Animals
School of Life Sciences
Sun Yat-sen University
Guangzhou 510275
China
机构
关键词
fish; growth hormone; receptor; signal transduction;
D O I
暂无
中图分类号
S917.4 [水产动物学];
学科分类号
0908 ;
摘要
In teleosts, growth hormone (GH) production is governed by multiple neuroendocrine factors from the hypothalamus and other regulators from the pituitary and peripheral organs. Exploring the principles followed by pituitary somatotropes when differentiating and integrating the signals from these regulators at the cellular and intracellular level is essential for understanding the endocrine regulation network of growth hormone synthesis and secretion in fish. This paper discusses recent advances in the action mechanisms of GH regulation factors, including the neuroendocrine regulators, pituitary level factors and peripheral factors, primarily involved in their receptor systems as well as in post-receptor signal transduction pathways.
引用
收藏
页码:462 / 470
页数:9
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