恶性肿瘤化疗药物的体外敏感试验

被引：6

作者：

李珊珊

裘宋良

机构：

[1] 河南省医学科学研究所肿瘤病理室郑州

来源：

癌症 | 1993年 / 06期

关键词：

微孔板法; 单层培养; 体外敏感试验; 体外药敏; 敏感性; 肿瘤病人; 存活细胞; 琼脂; 细胞悬液; 药敏试验; 试管法; 药物敏感;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

<正> 肿瘤病人对化疗的反应各异,即使肿瘤的组织学类型相同,仍存在差异。30年来人们作了多方面的尝试,企图建立体外检测方法来预测病人对抗瘤药物的敏感性及抵抗性。将病人的肿瘤标本进行体外培养,采用与抗生素敏感试验类似的方法进行药敏试验。这些方法可分为非集落形成系和集落形成系两大类。一、非集落形成系 Wright首先提出将病人自己的肿瘤怍体外短期培养,进行化疗药物敏感试验。 (一)单层培养(试管法及微孔板法): 1.试管单层法:将肿瘤组织剪碎、胰酶消化,再经滤过、离心、再悬浮,取一部分悬液加台盼蓝镜

引用

页码：547 / 549

页数：3

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