人参皂苷抗肝纤维化作用机制研究进展

被引:18
作者
孙媛媛 [1 ]
赵玉洁 [2 ]
赵金畅 [2 ]
周官红 [2 ]
海龙 [2 ]
姜娜 [2 ]
苏光悦 [1 ]
赵余庆 [1 ,3 ]
机构
[1] 沈阳药科大学
[2] 沈阳药科大学功能食品与葡萄酒学院
[3] 沈阳药科大学基于靶点的药物设计与研究教育部重点实验室
关键词
人参皂苷; 天然产物; 抗肝纤维化; 作用机制; 基质金属蛋白酶抑制剂-1; 抗氧化; 免疫调节;
D O I
暂无
中图分类号
R285 [中药药理学];
学科分类号
100806 [中药药理学];
摘要
人参皂苷是一类重要的天然产物,在自然界中分布广泛,是多种药用植物中的主要活性成分,具有多种生理活性。研究发现,人参皂苷在肿瘤疾病治疗中取得很大进展,同时在抗肝纤维化方面也有显著的作用。因此人参皂苷对肝纤维化的治疗具有重要的应用价值。对人参皂苷的抗肝纤维化作用机制进行综述,以便为今后进一步的研究提供理论依据。
引用
收藏
页码:1912 / 1915
页数:4
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