正确认识自身免疫性癫痫与自身免疫性脑炎的关系

被引：14

作者：

余年

狄晴

机构：

[1] 南京医科大学附属脑科医院神经内科

来源：

中华神经科杂志 | 2020年 / 53卷 / 02期

关键词：

癫痫; 神经系统自身免疫疾病; 脑炎; 诊断, 鉴别;

D O I：

暂无

中图分类号：

R742.9 []; R742.1 [癫痫];

学科分类号：

100204 [神经病学];

摘要：

自身免疫性癫痫与自身免疫性脑炎均是近年来随着神经免疫学发展而提出的临床新概念。对于伴有癫痫样发作、抗神经元抗体阳性的患者, 诊断为自身免疫性脑炎还是自身免疫性癫痫, 目前还存在争议和误区。由于二者存在部分共同的抗神经元抗体, 且临床表现有一定重叠性, 如癫痫的耐药性、合并认知功能损害等, 常被临床所混淆, 造成了不必要的过度抗癫痫治疗。笔者从二者临床概念、流行病学、发病机制及相关危险因素、临床表现、辅助检查、治疗和预后对二者区别和联系进行了释义。

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