单核细胞趋化蛋白-1和糖尿病肾病

被引:9
作者
包艳
李竞
甘佩珍
机构
[1] 湖北医科大学附属第一医院!湖北武汉
关键词
糖尿病; 糖尿病肾病; 单核细胞趋化因子;
D O I
暂无
中图分类号
R587.2 [糖尿病性昏迷及其他并发症];
学科分类号
摘要
糖尿病肾病 (DN)往往存在着血糖、血脂的代谢紊乱及某些细胞因子 (白介素 1、肿瘤坏死因子 α)和血管紧张素Ⅱ水平的升高 ,这些改变均可使体内单核细胞趋化因子 1(MCP 1)水平上升。MCP 1是一种对单核细胞有强烈趋化作用的细胞因子 ,它的增多使肾小球中单核细胞浸润 ,导致细胞外基质在肾小球和肾小管中堆积。因此MCP 1在DN的发生、发展中起重要作用。
引用
收藏
页码:3 / 5
页数:3
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