药物洗脱支架术后再内皮化延迟与晚期血栓形成

被引：5

作者：

张琳

张瑞岩

机构：

[1] 上海交通大学医学院附属瑞金医院心脏科

来源：

国际心血管病杂志 | 2009年 / 36卷 / 02期

关键词：

再内皮化; 晚期血栓; 药物支架; 内皮祖细胞;

D O I：

暂无

中图分类号：

R543 [血管疾病];

学科分类号：

摘要：

药物洗脱支架能有效减少支架再狭窄和靶血管再次血运重建,然而,与金属裸支架比较,药物洗脱支架术后晚期血栓发生率呈上升趋势。研究显示支架术后再内皮化延迟与晚期血栓发生密切相关。内皮化程度是组织学上预测支架晚期血栓发生的重要指标,而内皮祖细胞是再内皮化过程的关键因素之一。因此,促进内皮祖细胞再内皮化可显著降低由支架损伤引起的晚期血栓发生。

引用

页码：91 / 93+97 +97

页数：4

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