蜂蜜促进创伤愈合的免疫调控机制研究进展

被引：12

作者：

孔祥溢

关健

杨义

李永宁

马文斌

幸兵

王任直

机构：

[1] 中国医学科学院/北京协和医学院北京协和医院神经外科

来源：

医学研究杂志 | 2015年 / 10期

关键词：

蜂蜜; 创伤愈合; 细胞因子; 氧化应激; 炎性反应;

D O I：

暂无

中图分类号：

R269 [现代医学外科疾病];

学科分类号：

100210 [外科学];

摘要：

蜂蜜是地球上现存的最古老的食物之一,不仅具有很高的食用价值和药用价值,而且近年来在促进伤口愈合方面的作用越来越被重视。蜂蜜有着广谱的抗菌作用,这是其在促进伤口快速愈合方面独有的优势,其具体机制目前已被较为完备地阐述。近年来,蜂蜜在免疫调控方面的作用逐渐被发现并广泛探索,包括:1刺激或抑制单核-吞噬细胞合成与释放特定细胞因子,如肿瘤坏死因子(tumor necrosis factor,TNF)-α、白介素(interleukin,IL)-1β等;2调控氧化应激,如中性粒细胞释放活性氧簇(reactive oxygen species,ROSs)等;3调控角化细胞、成纤维细胞和内皮细胞等的炎性反应。对蜂蜜免疫调控作用的阐述和探索,对于更好地将蜂蜜应用于创伤的临床治疗至关重要。

引用

页码：18 / 21

页数：4

共 15 条

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