四环素类化合物抗肿瘤转移及其治疗其它疾病作用研究进展

被引:8
作者
韩韬
机构
[1] 青岛市第二人民医院!青岛
关键词
四环素类化合物; 肿瘤转移; 金属蛋白酶; 感染;
D O I
10.13461/j.cnki.wna.003448
中图分类号
R969 [临床药理学];
学科分类号
100602 ; 100706 ;
摘要
转移是恶性肿瘤的一个特点,它已成为治愈肿瘤的主要障碍。有报道四环素类化合物有络合金属离子的性质,故能抑制肿瘤间质金属蛋白酶的活性,从而为其在抗肿瘤转移、抑制肿瘤血管形成以及治疗其它疾病中拓宽了应用前景,但随着米诺环素等的大量应用,其副作用也时有报道。故本文旨在综述四环素类化合物在这方面的研究进展。
引用
收藏
页码:263 / 265
页数:3
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