妊娠期糖尿病基因多态性研究进展

被引:13
作者
武海荣 [1 ,2 ]
杨慧霞 [1 ]
机构
[1] 北京大学第一医院妇产科
[2] 中国航空工业中心医院妇产科
关键词
妊娠; 糖尿病; 基因表达; 多态性;
D O I
暂无
中图分类号
R714.2 [病理妊娠(异常妊娠)];
学科分类号
100211 [妇产科学];
摘要
由于基因分型及整组遗传基因鉴定技术的快速发展,已发现许多与2型糖尿病(type2 diabetes mellitus,T2DM)相关的易感基因及其多态性。与之相比,有关妊娠期糖尿病(gestational diabetes mellitus,GDM)的遗传基础研究较少。GDM发病机制与T2DM相似,其发病率近年逐年上升引起广泛关注。普遍认为,GDM是遗传和环境因素共同作用引起的临床综合征。对GDM的遗传基因及其多态性进行初步探讨,发现了一些GDM的易感基因。
引用
收藏
页码:20 / 22+26 +26
页数:4
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