活血化瘀复方和川芎嗪抑制血栓素A2生物合成的研究

被引：22

作者：

吴余升

陈可冀

机构：

[1] 中医研究院西苑医院,中医研究院西苑医院,

来源：

中西医结合杂志 | 1985年 / 03期

关键词：

川芎嗪; 活血化瘀复方; 合成酶; 连接酶; 川芍嗓; TXA; A2; 血栓素; 微粒体; 生化反应; 生物合成;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

本文报道了活血化瘀复方和川芎嗪对促血栓物质——血栓素 A2（TXA2）生物合成的影响及其作用机理。方法系采用放射薄层层析扫描、放射自显影及放射免疫测定等同位素技术。结果表明:活血化瘀复方和川芎嗪均有抑制肾髓质微粒体合成 TXA2的作用,这种抑制作用的机理,主要是选择性地抑制了 TXA2合成酶的活力,而对环氧化酶活力影响不明显。

引用

页码：169 / 171+133 +133

页数：4

共 7 条

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