心肌缺血再灌注损伤动物模型建立的主要影响因素

被引：12

作者：

关雷 ^{[1
]}

金英

王永安 ^{[2
]}

机构：

[1] 辽宁医学院基础学院

[2] 军事医学科学院毒物药物研究所

来源：

国际药学研究杂志 | 2009年 / 36卷 / 06期

关键词：

心肌缺血再灌注损伤; 动物模型; 影响因素;

D O I：

10.13220/j.cnki.jipr.2009.06.004

中图分类号：

R541 [心脏疾病]; R-332 [医用实验动物学];

学科分类号：

1002 ; 100201 ; 1001 ;

摘要：

心肌缺血再灌注损伤模型系模拟人心肌梗死及其再灌注治疗,研究缺血预适应机制,评价抗心肌缺血及心律失常药物疗效常用的动物模型。本文从冠状动脉血管结扎部位、进针深浅度和结扎松紧度等多个方面阐述了影响心肌缺血再灌注损伤实验动物模型建立的主要因素。

引用

页码：423 / 425+430 +430

页数：4

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