炎症反应影响甲状腺激素水平变化的机制

被引：6

作者：

赵露茜

刘志锋

苏磊

机构：

[1] 广州军区广州总医院重症医学科

[2] 广州市第一人民医院老年病科

[3] 广州军区广州总医院全军热区创伤救治与组织修复重点实验室

来源：

中国危重病急救医学 | 2012年 / 08期

关键词：

炎症反应; 甲状腺激素;

D O I：

暂无

中图分类号：

R363 [病理生理学];

学科分类号：

100104 ;

摘要：

炎症反应是机体对病原微生物感染、创伤、变态反应等发生的组织细胞反应,主要是指从细胞损害开始直到组织细胞修复全过程的病理生理变化。在炎症反应中,炎症介质如白细胞介素-6（IL-6）等能降低外周血甲状腺激素（TH）的水平。以往有研究认为,血清中游离甲状腺激素（FT4）和炎症细胞因子间存在一个互相影响的负反馈机制。那么,究竟炎症反应是如何影响TH水平变化的呢?现就炎症对TH表达、分泌的直接作用机制,以及炎症发生后TH的血浆转运、组织摄取和代谢等环节的调节机制进行综述。

引用

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