致炎细胞因子在骨性关节炎病理生理中的作用

被引：51

作者：

张洪亮

王文波

李明宇

李进取

史雪峰

机构：

[1] 哈尔滨医科大学附属第一临床医学院骨科

来源：

现代生物医学进展 | 2014年 / 14卷 / 05期

关键词：

骨性关节炎; 细胞因子; 白介素; 肿瘤坏死因子; 抗致炎细胞因子;

D O I：

10.13241/j.cnki.pmb.2014.05.052

中图分类号：

R684.3 [关节炎];

学科分类号：

100220 [骨科学];

摘要：

骨性关节炎(OA)是一种退行性病变,表现为关节软骨破坏,关节边缘骨赘形成,并伴有不同程度滑膜炎症,其病因学和发病机制还不是十分清楚。研究表明致炎细胞因子在骨性关节炎病发病的病理生理过程中起着重要的作用。本综述讨论目前关于致炎细胞因子在OA病理生理中的作用机制以及抗致炎细胞因子在治疗OA中的新进展。

引用

页码：989 / 992

页数：4

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