共 7 条
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One year of sitagliptin treatment protects against islet amyloid-associated β-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice
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AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM,
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:E475-E484
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Reduction of Oxidative Stress and Inflammation by Blunting Daily Acute Glucose Fluctuations in Patients With Type 2 Diabetes[J] . Maria Rosaria Rizzo,Michelangela Barbieri,Raffaele Marfella,Giuseppe Paolisso. Diabetes Care . 2012 (10)
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Vildagliptin preserves the mass and function of pancreatic β cells via the developmental regulation and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes[J] . S. Hamamoto,Y. Kanda,M. Shimoda,F. Tatsumi,K. Kohara,K. Tawaramoto,M. Hashiramoto,K. Kaku. Diabetes Obes Metab . 2012 (2)
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Vildagliptin selectively ameliorates GLP-1, GLUT4, SREBP-1c mRNA levels and stimulates β-Cell proliferation resulting in improved glucose homeostasis in rats with streptozotocin-induced diabetes[J] . Atul Sureshrao Akarte,B.P. Srinivasan,Sonia Gandhi. Journal of Diabetes and Its Complications . 2012 (4)
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Chronic administration of alogliptin, a novel, potent, and highly selective dipeptidyl peptidase-4 inhibitor, improves glycemic control and beta-cell function in obese diabetic ob/ob mice[J] . Yusuke Moritoh,Koji Takeuchi,Tomoko Asakawa,Osamu Kataoka,Hiroyuki Odaka. European Journal of Pharmacology . 2008 (2)
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DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with β-cell-specific overexpression of human islet amyloid polypeptide[J] . Regulatory Peptides . 2007 (1)