视黄醇结合蛋白4与代谢异常关系的研究进展

被引：5

作者：

刘晓华

魏丽

机构：

[1] 上海市糖尿病临床医学中心上海市糖尿病研究所上海交通大学附属第六人民医院内分泌科

来源：

中国实用内科杂志 | 2010年 / 30(S1)卷 / S1期

关键词：

视黄醇结合蛋白4; 肥胖; 脂肪肝; 代谢异常;

D O I：

暂无

中图分类号：

R589 [代谢病];

学科分类号：

摘要：

视黄醇结合蛋白4(RBP4)是近年来新发现的脂肪细胞因子,不仅参与了糖脂代谢的紊乱,在肥胖人群中显著升高,而且与代谢综合征及其组分以及脂联素密切相关,并且在内脏脂肪细胞功能紊乱和动脉粥样硬化性血管病变中起着重要的媒介作用。研究发现,RBP4与丙型肝炎病毒和非酒精性脂肪肝病变以及肾脏疾病的终末状态有着密切的关系。此外,RBP4在妊娠糖尿病、多囊卵巢综合征等性激素相关性疾病的发生机制中亦起着不可磨灭的作用。

引用

页码：77 / 79

页数：3

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