抑制NF-κB激活途径治疗IBD的进展

被引：2

作者：

陈佳婕

钟良

机构：

[1] 复旦大学附属华山医院消化科

来源：

国际消化病杂志 | 2009年 / 29卷 / 01期

关键词：

炎症性肠病; 抑制; 核因子-κB; 药物治疗;

D O I：

暂无

中图分类号：

R574 [肠疾病];

学科分类号：

1002 ; 100201 ;

摘要：

IBD患者肠道黏膜免疫反应异常,NF-κB是参与调控肠道免疫炎性反应的关键因子之一。现已证明,多种IBD临床治疗用药,如糖皮质激素、5-氨基水杨酸、抑制性细胞因子等的药理作用均与抑制NF-κB激活途径有关。此文从NF-κB在IBD发病机制上的作用入手,总结了目前在营养素治疗、激素治疗、中药治疗及其他新药对抑制NF-κB激活途径治疗IBD的研究。

引用

页码：65 / 67

页数：3

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