步行试验评价阿托伐他汀钙改善心功能衰竭转归初步观察

被引：6

作者：

乔延国 ^{[1
]}

黄志刚 ^{[2
]}

梁立武 ^{[1
]}

机构：

[1] 武警总医院干一科

[2] 解放军医院内科

来源：

实用医学杂志 | 2009年 / 25卷 / 07期

关键词：

心力衰竭,充血性; 6分钟步行试验; 阿托伐他汀钙; 心脏利钠肽; 运动耐量;

D O I：

暂无

中图分类号：

R541.6 [血液循环衰竭];

学科分类号：

摘要：

目的:以6min步行试验评价阿托伐他汀钙治疗慢性充血性心力衰竭(CHF)患者后血浆脑利钠肽(BNP)水平的动态变化,探讨阿托伐他汀钙对患者运动耐量及心脏内分泌的病理生理影响。方法:随机入选116例扩张性心肌病伴CHF患者,其中阿托伐他汀钙组59例,另57例为对照组。Bittner方案行6min步行试验。放射免疫法测定BNP。结果:阿托伐他汀钙治疗6个月后,患者症状、运动耐量明显改善,同时血浆BNP水平明显降低。结论:CHF患者接受阿托伐他汀钙治疗后能缓解心衰症状、提高运动耐量,而且显著改善心脏内分泌功能,这种心脏内分泌变化可能有助于心衰预后。

引用

页码：1130 / 1132

页数：3

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