慢性疼痛治疗药物的研究进展

被引:11
作者
贾立华
高永良
王世岭
宫泽辉
机构
[1] 中国人民解放军医院药剂科,军事医学科学院毒物药物研究所,中国人民解放军医院药剂科,军事医学科学院毒物药物研究所北京,北京,北京,北京
关键词
慢性疼痛; 镇痛药; 药物治疗;
D O I
10.13220/j.cnki.jipr.2004.02.008
中图分类号
R971 [神经系统药物];
学科分类号
1007 ;
摘要
慢性疼痛是一种长期以来威胁着人类健康的病症 ,由于其病理机制的复杂性 ,对于慢性疼痛的药物治疗始终是人们研究的重点和难点。本文从烟碱受体、毒蕈碱受体和腺苷A1受体激动剂 ,激肽受体、兴奋性氨基酸受体、神经生长因子受体和内皮素受体拮抗剂 ,环氧合酶、NO合酶和腺苷激酶抑制剂等几个类型综述了慢性疼痛治疗药物的开发现状 ,并叙述了镇痛药的联合用药及剂型的应用 ,展望了镇痛药的开发前景。
引用
收藏
页码:89 / 93
页数:5
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