四种拟除虫菊酯类农药的环境雌激素活性研究

被引:36
作者
邴欣
汝少国
机构
[1] 中国海洋大学海洋生命学院
关键词
环境雌激素; 拟除虫菊酯农药; 卵黄原蛋白; 生殖腺指数; γ-谷氨酰转移酶; 乳酸脱氢酶;
D O I
暂无
中图分类号
X592 [农用化学物质、有毒化学物质污染及其防治];
学科分类号
083001 [环境科学];
摘要
将金鱼(Carassius auratus)分别暴露于0.1mg/L甲氰菊酯、氰戊菊酯、溴氰菊酯和0.5mg/L氯氰菊酯21d后,尾静脉取血,离心分离获得血浆,利用Western-blot方法检测金鱼血浆中是否有卵黄原蛋白产生,同时测定金鱼生殖腺指数、γ-谷氨酰转移酶和乳酸脱氢酶活性.结果表明,对照组雄性金鱼血浆中未检测到卵黄原蛋白,4种拟除虫菊酯农药均能诱导雄性金鱼分泌卵黄原蛋白,而且溴氰菊酯和氯氰菊酯明显降低了雄鱼生殖腺指数,4种农药均能够明显抑制精巢γ-谷氨酰转移酶和乳酸脱氢酶活性.由此可见,4种拟除虫菊酯类农药具有潜在的环境雌激素活性和生殖毒性.
引用
收藏
页码:152 / 156
页数:5
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