1,3,4,6-四-O-乙酰基-β-D-氨基葡萄糖的合成

被引:12
作者
许金峰
方志杰
巨长丽
机构
[1] 南京理工大学化工学院
[2] 南京理工大学化工学院 江苏南京
[3] 江苏南京
关键词
D-氨基葡萄糖盐酸盐; 保护; 脱保护; 合成;
D O I
10.15952/j.cnki.cjsc.2003.05.003
中图分类号
O636.1 [高分子多聚糖];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
分别用对甲氧基苯甲醛和苯甲醛保护D 氨基葡萄糖的氨基 ,再将羟基用乙酰基保护 ,以氯化氢脱去氨基上的保护基团 ,最后脱去氯化氢得到 1,3,4 ,6 四 O 乙酰基 β D 氨基葡萄糖。两种方法的总产率分别为 5 9%和6 1%。道关键中间体 3b未见报 ,其结构经1HNMR表征
引用
收藏
页码:379 / 380+433 +433
页数:3
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