肠道菌群在机体免疫调节功能中的作用

被引:19
作者
杨雪菲
漆艳娥
太珍珍
唐立
机构
[1] 大连医科大学微生态学教研室
关键词
肠道菌群; 黏膜免疫; 细胞免疫; 免疫调节;
D O I
暂无
中图分类号
R333.3 [肠的生理];
学科分类号
100123 [人体微生态学];
摘要
肠道菌群被称为是人体的一个重要"器官",具有数量庞大、种类繁多等特点,对人体具有重要的生理与病理意义。肠道菌群对机体免疫功能的影响日益受到广泛关注。本文主要就肠道菌群对肠道形态及功能、肠道黏膜免疫系统以及肠道外免疫系统三个方面的影响进行综述。
引用
收藏
页码:979 / 983
页数:5
相关论文
共 59 条
[1]
Erratum: Immune adaptations that maintain homeostasis with the intestinal microbiota.[J].Lora V. Hooper;Andrew J. Macpherson.Nature Reviews Immunology.2015, 5
[2]
The Gut Microbiome.[J].Giovanni C. Actis.Inflammation & Allergy-Drug Targets.2014, 4
[3]
The presence, function and regulation of IL-17 and Th17 cells in periodontitis [J].
Cheng, Wan-Chien ;
Hughes, Francis J. ;
Taams, Leonie S. .
JOURNAL OF CLINICAL PERIODONTOLOGY, 2014, 41 (06) :541-549
[4]
The Microbiome in Infectious Disease and Inflammation.[J].Kenya Honda;Dan R. Littman.Annual Review of Immunology.2012, 1
[5]
Development of the Human Gastrointestinal Microbiota and Insights From High-Throughput Sequencing [J].
Dominguez-Bello, Maria Gloria ;
Blaser, Martin J. ;
Ley, Ruth E. ;
Knight, Rob .
GASTROENTEROLOGY, 2011, 140 (06) :1713-1719
[6]
How bugs and men live in harmony. Role of defensins in gut microbial composition and Th17 development [J].
Bos, Nico A. ;
Salzman, Nita .
IMMUNOLOGY LETTERS, 2011, 138 (01) :25-27
[7]
Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis [J].
Hill, D. A. ;
Hoffmann, C. ;
Abt, M. C. ;
Du, Y. ;
Kobuley, D. ;
Kirn, T. J. ;
Bushman, F. D. ;
Artis, D. .
MUCOSAL IMMUNOLOGY, 2010, 3 (02) :148-158
[8]
Enteric defensins are essential regulators of intestinal microbial ecology [J].
Salzman, Nita H. ;
Hung, Kuiechun ;
Haribhai, Dipica ;
Chu, Hiutung ;
Karlsson-Sjoeberg, Jenny ;
Amir, Elad ;
Teggatz, Paul ;
Barman, Melissa ;
Hayward, Michael ;
Eastwood, Daniel ;
Stoel, Maaike ;
Zhou, Yanjiao ;
Sodergren, Erica ;
Weinstock, George M. ;
Bevins, Charles L. ;
Williams, Calvin B. ;
Bos, Nicolaas A. .
NATURE IMMUNOLOGY, 2010, 11 (01) :76-U1
[9]
Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective..[J].Weaver Casey T;Hatton Robin D.Nature reviews. Immunology.2009, 12
[10]
Prevention of TNBS-Induced Colitis by Different Lactobacillus and Bifidobacterium Strains Is Associated with an Expansion of γδT and Regulatory T Cells of Intestinal Intraepithelial Lymphocytes [J].
Roselli, Marianna ;
Finamore, Alberto ;
Nuccitelli, Silvia ;
Carnevali, Paola ;
Brigidi, Patrizia ;
Vitali, Beatrice ;
Nobili, Fabio ;
Rami, Rita ;
Garaguso, Ivana ;
Mengheri, Elena .
INFLAMMATORY BOWEL DISEASES, 2009, 15 (10) :1526-1536