颈动脉分流造成大鼠脑缺血再灌流损伤的动物模型

被引：3

作者：

田鹤邨

谢群

陈前芬

机构：

[1] 蚌埠医学院病理生理学教研室

[2] 蚌埠医学院病理学教研室

来源：

蚌埠医学院学报 | 1993年 / 02期

关键词：

脑缺血; 颈总动脉结扎; 再灌流损伤; 脑电图; 超微结构; 大白鼠;

D O I：

10.13898/j.cnki.issn.1000-2200.1993.02.019

中图分类号：

学科分类号：

摘要：

结扎大鼠左侧颈总动脉,从右侧颈总动脉远心端放血,放出的血液由股静脉输回体内,持续放血时间分别为30、60、90和120min;然后解除左侧颈总动脉结扎,同时停止放血,继续观察60min。动态观察脑电图、瞳孔颜色和动脉血压,进行光镜和电镜检查。结果发现在放血15min后,脑电波变平,以后未见恢复;随着缺血时间延长,缺血性损害相应加重,再灌后进一步恶化。

引用

页码：109 / 112+2 +2

页数：5

共 7 条

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