用2.2.15细胞株筛选抗乙型肝炎病毒药物的研究

被引:15
作者
米抒
傅希贤
张国庆
张乃临
机构
[1] 北京医科大学第一医院传染科
关键词
乙型肝炎病毒; 药物筛选; 抗病毒剂;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
以乙型肝炎病毒(HBV)DNA转染细胞株2.2.15细胞培养上清液中HBsAg和HBeAg滴度作为药物抗HBV效果的评价指标,对43种药物的抗HBV作用进行了评价。同时,应用四甲基偶氮唑盐(MTT)比色分析法检测药物的细胞毒性。结果提示抗肝Ⅰ号、抗肝Ⅱ号、复方黄芪浸膏片水提取液,复方仙茅浸膏片水提取液,518BII-甲-6等5种药物可能为有潜力的抗HBV药物。
引用
收藏
页码:612 / 615 +640
相关论文
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