急性胃肠功能障碍的认知与困惑

被引:36
作者
虞文魁
机构
[1] 南京大学医学院附属金陵医院(南京军区南京总医院)解放军普通外科研究所SICU
关键词
急性胃肠功能障碍; 多器官功能障碍; 急性胃肠损伤;
D O I
10.16571/j.cnki.1008-8199.2015.05.007
中图分类号
R57 [消化系及腹部疾病]; R459.7 [急症、急救处理];
学科分类号
100201 [内科学]; 100231 [临床病理学];
摘要
<正>早在20世纪50年代,肠道在系统性脓毒症中的作用就被提出[1]。自20世纪80年代以来,胃肠道在全身炎症反应及多器官功能障碍(multiple organ dysfunction syndrome,MODS)中的作用越来越受到人们关注,并被认为是"应激反应的中心"和"MODS的发动机"。研究显示约62%的ICU患者会出现至少一种胃肠功能障碍的症状,并且越来越多的证据表明,胃肠功能障碍的发生与患者的预
引用
收藏
页码:449 / 453
页数:5
相关论文
共 21 条
[1]
Effects of glutamine supplementation on gut barrier, glutathione content and acute phase response in malnourished rats during inflammatory shock [J].
Belmonte, Liliana ;
Coeffier, Moise ;
Le Pessot, Florence ;
Miralles-Barrachina, Olga ;
Hiron, Martine ;
Leplingard, Antony ;
Lemeland, Jean-Francois ;
Hecketsweiler, Bernadette ;
Daveau, Maryvonne ;
Ducrotte, Philippe ;
Dechelotte, Pierre .
WORLD JOURNAL OF GASTROENTEROLOGY, 2007, 13 (20) :2833-2840
[2]
加强对肠屏障功能障碍的研究 [J].
黎介寿 .
中华医学杂志, 1999, (08)
[3]
Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems [J].
Blaser, Annika Reintam ;
Malbrain, Manu L. N. G. ;
Starkopf, Joel ;
Fruhwald, Sonja ;
Jakob, Stephan M. ;
De Waele, Jan ;
Braun, Jan-Peter ;
Poeze, Martijn ;
Spies, Claudia .
INTENSIVE CARE MEDICINE, 2012, 38 (03) :384-394
[4]
Acute intestinal failure in critically ill patients: is plasma citrulline the right marker? [J].
Piton, Gael ;
Manzon, Cyril ;
Cypriani, Benoit ;
Carbonnel, Franck ;
Capellier, Gilles .
INTENSIVE CARE MEDICINE, 2011, 37 (06) :911-917
[5]
Early enteral nutrition, provided within 24 h of injury or intensive care unit admission, significantly reduces mortality in critically ill patients: a meta-analysis of randomised controlled trials [J].
Doig, Gordon S. ;
Heighes, Philippa T. ;
Simpson, Fiona ;
Sweetman, Elizabeth A. ;
Davies, Andrew R. .
INTENSIVE CARE MEDICINE, 2009, 35 (12) :2018-2027
[6]
Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition: Executive Summary*.[J].Robert G. Martindale;Stephen A. McClave;Vincent W. Vanek;Mary McCarthy;Pamela Roberts;Beth Taylor;Juan B. Ochoa;Lena Napolitano;Gail Cresci.Critical Care Medicine.2009, 5
[7]
Gastrointestinal Failure score in critically ill patients: a prospective observational study [J].
Reintam, Annika ;
Parm, Pille ;
Kitus, Reet ;
Starkopf, Joel ;
Kern, Hartmut .
CRITICAL CARE, 2008, 12 (04)
[8]
Gastrointestinal motility in acute illness.[J].Sonja Fruhwald;Peter Holzer;Helfried Metzler.Wiener klinische Wochenschrift.2008, 1
[9]
The gut is a motor of organ system dysfunction [J].
Leaphart, Cynthia L. ;
Tepas, J. J., III .
SURGERY, 2007, 141 (05) :563-569
[10]
Protective Effects of Hyperoxygenated Solution Preconditioning on Intestinal Ischemia–Reperfusion Injury in Rabbits.[J].Changjun Gao;Wei Chai;Lixian Xu;Guihe Zhang;Hui Zhang;Lichun Han;Xude Sun.Journal of Surgical Research.2006, 2