接触性热痛诱发电位检测方法的建立

被引：15

作者：

郑菊阳

徐迎胜

张朔

张俊

康德碹

樊东升

机构：

[1] 北京大学第三医院神经内科

来源：

中华神经科杂志 | 2007年 / 40卷 / 02期

关键词：

热; 疼痛感受器; 诱发电位,躯体感觉; 神经传导; 神经纤维;

D O I：

暂无

中图分类号：

R741 [神经病学];

学科分类号：

100204 [神经病学];

摘要：

目的建立接触性热痛诱发电位(CHEP)的检测方法,估测介导此诱发电位的外周神经传导速度。方法受试者取卧位,应用 CHEP 刺激器,于两个强度水平(49.5℃和54.5℃)应用可调节脉冲,刺激部位为鱼际肌、手背、前臂的掌侧面。受试者在每次刺激后,按照视觉模拟评分标准对刺激强度分级。以 Keypoint 仪器记录,记录点为 Cz 和 Pz。测定刺激强度和疼痛分级的关系、诱发电位的主要成分及外周神经传导速度。结果刺激强度和疼痛分级的关系为:49.5℃和54.5℃刺激鱼际肌皮肤,疼痛分级分别为(3.2±0.3)、(4.4±0.5)级;54.5℃刺激手背和前臂掌侧面皮肤,疼痛分级分别为(6.3±0.8)、(7.2±0.5)级。于记录点记录到3个主要成分:Cz/N550、Cz/P750和 Pz/P1000。介导此诱发电位的外周神经传导速度分别为(12.9±7.5)、(1.7±0.4)m/s,分别与 Aδ纤维和 C 纤维的传导速度相对应。结论 CHEP 能较为稳定、可靠地引出,介导此诱发电位的外周神经为Aδ纤维和 C 纤维。

引用

页码：129 / 132

页数：4

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