早期（T1N0M0）非小细胞肺癌外科治疗的探讨

被引：4

作者：

李厚怀

沈振亚

机构：

[1] 东南大学附属南京江北人民医院胸外科

[2] 苏州大学附属第一医院心胸外科

来源：

中华胸心血管外科杂志 | 2003年 / 04期

关键词：

癌; 非小细胞肺; 肺切除术; 肿瘤复发; 局部;

D O I：

暂无

中图分类号：

R734.2 [肺肿瘤];

学科分类号：

摘要：

目的　探讨肺叶切除术和楔形切除术对早期 (T1N0 M0 )非小细胞肺癌 (NSCLC)的疗效。方法　分析 10 9例早期 (T1N0 M0 )NSCLC病例的手术效果 ,其中楔形切除术 5 1例 (开胸组 2 1例 ,胸腔镜组 30例 ) ,肺叶切除术 5 8例 ;包括各治疗组间对术后并发症发生率、病死率、术后复发率、生存率及肺功能的评估。结果　各治疗组间肿瘤的组织类型、术后并发症发生率和病死率及后期肺功能差异无显著性。楔形切除组年龄偏大 ,慢性阻塞性肺病 (COPD)发病率高 ,肺功能较差 ,与肺叶切除组相比 ,平均住院日明显减少 ,局部复发率增高 ,差异有统计学意义。 1年生存率各组相似 (开胸楔形切除组 94 % ,胸腔镜楔形切除组95 % ,肺叶切除组 91% ) ,5年生存率开胸楔形切除组 5 8% ,胸腔镜楔形切除组 6 5 % ,肺叶切除组 70 % ,差异有统计学意义 (P =0 0 2 )。结论　对有心肺功能损害的早期NSCLC病人 ,楔形切除术是一种可行的外科治疗 ;但由于局部复发率较高 ,只要病人心肺功能耐受 ,仍应首选肺叶切除术。

引用

页码：28 / 30

页数：3

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