脑缺血损伤机制和治疗策略研究进展

被引:19
作者
唐康
张均田
机构
[1] 中国医学科学院中国协和医科大学药物研究所!北京
关键词
缺血性中风; 谷氨酸; 凋亡; 炎症; 自由基; 线粒体; 腺苷;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
1002 ;
摘要
缺血性中风是目前严重威胁人类健康的几种疾病之一 ,对其损伤机制的研究正逐步深入 ,除兴奋性毒性、钙超载外 ,还包括细胞凋亡、炎症、自由基、一氧化氮以及线粒体的损伤 ,同时 ,机体亦有内在的保护机制。尽管临床治疗仍以溶栓为主 ,谷氨酸受体拮抗剂、钙拮抗剂、自由基清除剂和半胱天冬酶抑制剂的保护作用的研究已取得了进展
引用
收藏
页码:809 / 813
页数:5
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