膝骨关节炎再生修复治疗新方法研究进展

被引：23

作者：

张中原 ^{[1
,2
]}

余丽梅 ^{[1
,2
,3
]}

王信 ^{[3
,4
]}

机构：

[1] 遵义医学院附属医院贵州省细胞工程重点实验室

[2] 遵义医学院附属医院贵州省组织损伤修复与再生医学协同创新中心

[3] 遵义医学院附属医院贵州省骨髓与羊膜间充质干细胞基础与临床研究科技创新人才团队

[4] 遵义医学院附属医院骨科

来源：

实用医学杂志 | 2018年 / 34卷 / 09期

关键词：

膝关节; 骨性关节炎; 再生; 修复;

D O I：

暂无

中图分类号：

R684.3 [关节炎];

学科分类号：

100220 [骨科学];

摘要：

膝骨关节炎(KOA)是最常见的关节退行性疾病,目前KOA的临床治疗包括抗炎镇痛药物、理疗、透明质酸局部注射和手术,以缓解临床症状与延缓病程进展或关节置换。随着疾病认识的深入、细胞工程技术与生物材料研究的进展,新兴的再生修复治疗应运而生,生长因子、血液成分提取物、干细胞或软骨细胞移植、干细胞来源外泌体及基因疗法,不但具有抗炎、免疫调节及促进血管再生,减轻关节损伤的作用,更为突出的是促进关节软骨再生修复。本文重点介绍了上述新方法的基础与临床研究进展。

引用

页码：1561 / 1564

页数：4

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