Raman spectroscopic identification of normal and malignant human stomach cells

被引：7

作者：

杨继朋 ^{[1
,2
]}

郭建宇 ^{[1
,2
]}

吴良平 ^{[1
,2
]}

孙真荣 ^{[1
,2
]}

蔡炜颖 ^{[1
,2
]}

王祖赓 ^{[1
,2
]}

机构：

[1] Key Laboratory of Optical and Magnetic Resonance Spectroscopy (East China Normal University),Ministry of Education

[2] Department of Physics,and Department of Chemistry,East China Normal University,Shanghai

来源：

Chinese Optics Letters | 2005年 / 12期

关键词：

Raman spectroscopic identification of normal and malignant human stomach cells;

D O I：

暂无

中图分类号：

R735.2 [胃肿瘤];

学科分类号：

100214 ;

摘要：

<正>Micro-Raman spectroscopy is employed to identify the normal and malignant human stomach cells. For the cancer cell, the reduced intensity of the Raman peak at 1250 cm-1 indicates that the protein secondary structure transforms from β-sheet or disordered structures to α-helical, while the increased intensity of the symmetric PO2 stretching vibration mode at 1094 cm-1 shows the increased DNA content. The ratio of the intensity at 1315 cm-1 to that at 1340-1 reduces from 1.8 for the normal cell to 1.1 for the cancer cell in the course of canceration, and the ratio of the intensity at 1655 cm-1 to that at 1450cm-1 increases from 1.00 for the cancer cell to 1.26 for the normal cell which indicates that the canceration of stomach cell may induce saturation of the lipid chain.

引用

页码：705 / 707

页数：3