TSC基因的生物学作用

被引：6

作者：

徐智芳

王建祥

机构：

[1] 中国医学科学院中国协和医科大学血液学研究所

来源：

医学分子生物学杂志 | 2008年 / 05期

关键词：

结节性硬化症; TSC基因; mTOR;

D O I：

暂无

中图分类号：

R593.2 [自身免疫性疾病、结缔组织疾病];

学科分类号：

100201 [内科学];

摘要：

TSC基因TSC1和TSC2分别编码蛋白hamartin和tuberin,最初在结节性硬化症中发现其存在突变,作为肿瘤抑制因子,除参与mTOR信号途径调节细胞的生长和增殖外,还参与细胞黏附,细胞内吞等过程的调节。

引用

收藏

页码：458 / 461

页数：4

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